Phosphate FS

Product Number : 1 5211

Description

Phosphorus is found in the body as phosphate, mainly as an inorganic material for bone, as well as in phospholipid cells and nucleic acids and adenosine triphosphate, which are involved in energy transfer. In plasma it is present as calcium phosphate; therefore, plasma phosphorus levels are strongly related to calcium levels. Measurement of phosphorus in serum and urine is mainly performed to detect disorders of the kidneys, bones and parathyroid glands. Elevated concentrations are found in renal failure, hypoparathyroidism, pseudo-hyperparathyroidism and loss of bone and cell calcium phosphate. Impairment occurs in malabsorption, hyperparathyroidism and vitamin D deficiency. Additional information can be obtained by adding calcium measurements.

Increased in

  • Renal insufficiency
  • Hypoparathyroidism
  • Childhood
  • Hypocalcemia
  • Excess intake of vitamin D
  • Acromegaly
  • Bone metastases
  • Sarcoidosis
  • Liver disease

Decreased in

  • Hyperparathyroidism (primary)
  • Vitamin D deficiency
  • Malabsorption
  • Administration of glucose (hyperalimentation)
  • Hyperinsulinism
  • Loss of phosphate in urine e.g. Fanconi syndrome
  • Diabetes ketoacidosis insulin treatment
  • Rickets
  • Protein loss enteropathy

Features

  • Ready to use reagent.
    Proline Phosphate FS comes in a liquid format which provides convenience for users as no reconstitution is required which helps reduce the risk of misdiagnosis.
  • Open system reagent, compatible with a wide range of instruments.
    Proline Phosphate FS reagent is suitable for various third-party analyzers such as Abbott, Advia, Cobas, Hitachi, Olympus, Response, TokyoBoeki, and Beckman Coulter.

Specification

  • UV photometric test with endpoint
  • No interference: ascorbic acid 30mg/dL, bilirubin 60mg/dL, hemoglobin 1000mg/dL, and lipemia up to triglycerides 2000mg/dL
  • The linearity measurement reaches 30 mg/dL, with a detection limit of 0.2 mg/dL

Calibrator

  • TruCal U

Control

  • TruLab N
  • TruLab P

Kit Lines

No. Catalog R1 R2 Kit Size
1 5211 99 10 920 4 x 34 mL 4 x 10 mL Proline® R-910

Reference Range

Serum / Plasma
Adults 2.6 mg/dL 0.84-1.45 mmol/L
Children / Teenager
1 – 30 day 3.9 – 7.7 mg/dL 1.25 – 2.50 mmol/L
1 – 12 month 3.5 – 6.6 mg/dL 1.15 – 2.15 mmol/L
1 – 3 year 3.1 – 6.0 mg/dL 1.00 – 1.95 mmol/L
4 – 6 years 3.3 – 5.6 mg/dL 1.05 – 1.80 mmol/L
7 – 9 years 3.0 – 5.4 mg/dL 0.95 – 1.75 mmol/L
10 – 12 years 3.2 – 5.7 mg/dL 1.05 – 1.85 mmol/L
13 – 15 years 2.9 – 5.1 mg/dL 0.95 – 1.65 mmol/L
16 – 18 years 2.7 – 4.9 mg/dL 0.85 – 1.60 mmol/L
Urine
Children and Adults 0.4 – 1.3 g/24h 12.9 – 42.0 mmol/24h

Each laboratory should check whether the reference range can be calculated for its patient population and determine its own reference range if necessary.