Description

Gamma-glutamyltransferase (gamma-GT/GGT), also called gamma-glutamyl transpeptidase, is an enzyme present in the liver and bile ducts and is the most sensitive indicator of hepatobiliary disease. Due to the high negative predictive value for these diseases, gamma-GT measurements are widely used to exclude the presence of diseases of liver or biliary origin. Together with other enzymes such as alanine aminotransferase (ALAT), aspartate aminotransferase (ASAT), and cholinesterase, gamma-GT is a potential marker for the differential diagnosis of liver disease.

Increased in

• Hepatobiliary disease
• History of alcohol consumption
• History of taking addictive drugs, e.g. phenytoin, phenobarbital
• Pancreatitis
• Myocardial infarction (4 – 10 days after)
• Cholestasis

Features

• Ready to use reagent.
  Proline Gamma-GT FS comes in a liquid format which provides convenience for users as no reconstitution is required which helps reduce the risk of misdiagnosis.
• Open system reagent, compatible with a wide range of instruments.
  Proline Gamma-GT FS reagent is suitable for various third party analyzers such as Abbott, Advia, Cobas, Hitachi, Olympus, Response, TokyoBoeki, and Beckman Coulter. 

Specification

• Kinetic photometric test according to Szasz / Persijn standardized IFCC (International Federation of Clinical Chemistry and Laboratory Medicine).
• Results according to IFCC are obtained using special factors or by using the calibrator values ​​given for the IFCC method.
• No interference: ascorbic acid 30mg/dL, bilirubin 4mg/dL, hemoglobin 500mg/dL, and lipemia up to 2000mg/dL triglycerides.
• Measurement linearity reached 15 mg/dL (18 – 1330 mol/L), with a lower limit of detection 0.2 mg/dL (17.7 mol/L).

Calibrator

• TruCal U

Control

• TruLab N
• TruLab P

Kit Lines